Download PDF by Ulf Landmesser, Helmut Drexler (auth.), Martial G. Bourassa,: Antioxidants and Cardiovascular Disease

By Ulf Landmesser, Helmut Drexler (auth.), Martial G. Bourassa, Jean-Claude Tardif (eds.)

ISBN-10: 0387295526

ISBN-13: 9780387295527

ISBN-10: 0387295534

ISBN-13: 9780387295534

Antioxidants and heart problems, moment version addresses a fancy yet very well timed and interesting challenge in cardiovascular drugs. it truly is written by way of famous specialists within the fields of atherosclerosis and antioxidants. it may be of curiosity not just to academicians but in addition to working towards physicians. the 1st 5 chapters overview the final techniques of oxidative tension and their dating to lipid metabolism, endothelial disorder, genetics and transcriptional elements. the subsequent seven chapters describe lately outlined markers of oxidative rigidity, pharmacological compounds with antioxidant task, normal antioxidants present in micronutrients and in nutrient-rich diets, and reports the new facts for his or her efficacy or loss of efficacy in sufferers with heart problems or cardiovascular hazard elements. The final seven chapters speak about the capability healing advantages of antioxidants in a few cardiovascular stipulations which come with atherosclerosis, restenosis after percutaneous coronary intervention, significant cardiovascular chance elements akin to high blood pressure, diabetes mellitus and dyslipidemia, and left ventricular disorder and congestive center failure.

Martial G. Bourassa, M.D. and Jean-Claude Tardif, M.D. are affiliated with the Montreal middle Institute, learn middle and division of drugs, college of medication, collage of Montreal, Montreal, Quebec, Canada.

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Extra resources for Antioxidants and Cardiovascular Disease

Example text

Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins. J Clin Invest 1979;64:743-50. Palinski W, Yla-Herttuala S, Rosenfeld ME et al. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis 1990;10:325-35. Rosenfeld ME, Palinski W, Yla-Herttuala S et al. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

Phagocytes and oxidative stress. Am J Med 2000;109:33-44. Cyrus T, Witztum JL, Rader DJ et al. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest 1999;103:1597-604. Cyrus T, Pratico D, Zhao L et al. Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E-deficient mice. Circulation 2001;103:2277-82. Steinberg D. At last, direct evidence that lipoxygenases play a role in atherogenesis. J Clin Invest 1999;103:1487-8.

Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein E-deficient mice. Circulation 2001;103:2277-82. Steinberg D. At last, direct evidence that lipoxygenases play a role in atherogenesis. J Clin Invest 1999;103:1487-8. Parthasarathy S, Santanam N, Ramachandran S et al. Oxidants and antioxidants in atherogenesis. An appraisal [In Process Citation]. J Lipid Res 1999;40:2143-57. Yla-Herttuala S, Rosenfeld M, Sigal E et al. Gene expression in macrophage-rich human atherosclerotic lesions.

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Antioxidants and Cardiovascular Disease by Ulf Landmesser, Helmut Drexler (auth.), Martial G. Bourassa, Jean-Claude Tardif (eds.)


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