Download e-book for iPad: Applications of Biotechnology in Cardiovascular Therapeutics by Kewal K. Jain

By Kewal K. Jain

ISBN-10: 161779239X

ISBN-13: 9781617792397

For physicians, surgeons, and scientists engaged on cardiovascular issues, Applications of Biotechnology in Cardiovascular Therapeutics serves as a useful reference via accumulating the fundamental writings of Dr. Kewal okay. Jain at the issues of biotechnology as they relate to heart problems. This thorough quantity comprises such topics as biotechnology and healing supply to the cardiovascular method, cell-selective designated drug supply, mobile and gene treatments, together with antisense and RNA interference, state-of-the-art gene remedy ways, in addition to custom-made cardiology as a manner of integrating new applied sciences into the choice of the very best remedy for a person sufferer. chosen references from contemporary literature are amassed for every bankruptcy, and the textual content is supplemented through quite a few necessary tables and figures.

Comprehensive and updated, Applications of Biotechnology in Cardiovascular Therapeutics might be greatly valuable for these operating in existence sciences and the pharmaceutical sciences, and the inclusion of a few fundamentals of cardiovascular ailments will vastly gain nonmedical readers as well.

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Extra resources for Applications of Biotechnology in Cardiovascular Therapeutics

Sample text

These include cardiac surgery, viral diseases, cardiotoxic chemotherapeutics, atherosclerosis of smaller coronary artery branches, environmental toxins such as carbon monoxide, hypoxia, and aging. 2. Those relevant to biotechnology are described in this book. Details of other measures for cardioprotection are beyond the scope of this book. The first strategy in cadioprotection is to remove the causes of ischemic heart disease; the second is to attenuate ongoing ischemic and reperfusion injury; the third is to prevent the progression of cardiac remodeling and chronic heart failure following ischemic injury.

Antioxidant properties of carvedilol can be used to minimize oxidative stress, a powerful inducer of mitochondrial permeability transition. Carvedilol has a positive impact of on the prognosis of patients with coronary heart disease (Carreira et al. 2006). Nebivolol is a selective b1 receptor blocker with nitric oxide-potentiating vasodilatory effect used for the treatment of hypertension as well as left ventricular 22 1 Cardiovascular Therapeutics failure. It avoids many of the side effects of other beta blockers that are caused by their blockade of b2 receptors.

2. Those relevant to biotechnology are described in this book. Details of other measures for cardioprotection are beyond the scope of this book. The first strategy in cadioprotection is to remove the causes of ischemic heart disease; the second is to attenuate ongoing ischemic and reperfusion injury; the third is to prevent the progression of cardiac remodeling and chronic heart failure following ischemic injury. For prevention of acute myocardial infarction, it is widely accepted to treat high-risk patients with aspirin and/or statins.

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Applications of Biotechnology in Cardiovascular Therapeutics by Kewal K. Jain


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